You can use pd.Series.isin.
For "IN" use: something.isin(somewhere)
Or for "NOT IN": ~something.isin(somewhere)
For example,
>>> df
countries
0 US
1 UK
2 Germany
3 China
>>> countries
['UK', 'China']
>>> df.countries.isin(countries)
0 False
1 True
2 False
3 True
Name: countries, dtype: bool
>>> df[df.countries.isin(countries)]
countries
1 UK
3 China
>>> df[~df.countries.isin(countries)]
countries
0 US
2 Germany