Is it okay for general applications to use the RuntimeError exception

Question

raise RuntimeError('config file is missing host address')

I've got some code with a couple of one-off situations like this and would prefer to avoid creating one-off exception classes for each of them. All the situations are fatal, and my goal is to get a clear message to the console. Basically I'm looking for something similar to the deprecated

raise 'config file is missing host address'